Piekarowicz Katarzyna

Piekarowicz Katarzyna Country: Poland
Laboratory webpage
E-mail: katarzyna.piekarowicz@uwr.edu.pl

Participation in Working Groups

  • WG3 - New methodologies to study mechanobiology of cells and tissues

Research Interests

I'm interested in nuclear proteins, especially lamins and emerin and they role in health and disease. My research projects focus on molecular background of laminopathies, lamins regulation and signalling as well as on therapeutic approach in Emery Dreifuss Muscular Dystrophy.

Technologies offered to other EuroCellNet participants

I have expertise in cell culture techniques such as primary and immortalized cell lines, transgenes expression, transfection techniques, viral vectors and live cell analysis. I work mostly with muscle cells. I also have experience with microscopy techniques, immunostaining, biochemistry analyses, gene expression measurements, flow cytometry, cloning and othe molecular biology techniques.

Technologies sought from other EuroCellNet participants

I'm interested in different aspects of cell nucleus and I'm especially interested in techniques focused on nuclear lamina, such as investigating interactions network and gene expression regulation.

Publications

Pałka M, Tomczak A, Grabowska K, Machowska M, Piekarowicz K, Rzepecka D, Rzepecki R (2018): „Laminopathies - what can humans learn from fruit fly" CMBL

Piekarowicz K, Machowska M, Dratkiewicz E, Lorek D, Madej-Pilarczyk A, Rzepecki R (2016): „The effects of the lamin A and its mutants on nuclear structure, cell proliferation, protein stability and mobility in embryonic cells.”, Chromosoma

Machowska M*, Piekarowicz K*, Rzepecki R (2015): „Regulation of lamin properties and functions – does phosphorylation do it all?” Open Biology (*equally contributed)

Zaremba-Czogalla M, Piekarowicz K, Wachowicz K, Kozioł K, Dubińska-Magiera M, Rzepecki R (2012): “The different function of single phosphorylation sites of Drosophila melanogaster lamin Dm and lamin C” PLoS One 7(2):e32649