Wilhelmsson Ulrika

Country: Sweden
E-mail: ulrika.wilhelmsson@neuro.gu.se

Participation in Working Groups

  • WG4 - Mechanobiological principles of rare and common diseases

Research Interests

My research focus is the role astrocyte in CNS disease; the role of astrocyte intermediate filament proteins in astrocyte activation in the diseased CNS and regeneration and plasticity of CNS.

Technologies offered to other EuroCellNet participants

Mouse models of CNS trauma and disease, mouse motor performance and congnitive tests.

Technologies sought from other EuroCellNet participants



Astrocytes negatively regulate neurogenesis through the Jagged1-mediated Notch pathway. Wilhelmsson U, Faiz M, de Pablo Y, Sjöqvist M, Andersson D, Widestrand A, Potokar M, Stenovec M, Smith PL, Shinjyo N, Pekny T, Zorec R, Ståhlberg A, Pekna M, Sahlgren C, Pekny M.

Stem Cells. 2012 Oct;30(10):2320-9. doi: 10.1002/stem.1196.PMID:22887872

Attenuating astrocyte activation accelerates plaque pathogenesis in APP/PS1 mice. Kraft AW, Hu X, Yoon H, Yan P, Xiao Q, Wang Y, Gil SC, Brown J, Wilhelmsson U, Restivo JL, Cirrito JR, Holtzman DM, Kim J, Pekny M, Lee JM.

FASEB J. 2013 Jan;27(1):187-98. doi: 10.1096/fj.12-208660.PMID:23038755

Heterogeneity of Notch signaling in astrocytes and the effects of GFAP and vimentin deficiency. Lebkuechner I, Wilhelmsson U, Möllerström E, Pekna M, Pekny M.

J Neurochem. 2015 Oct;135(2):234-48. doi: 10.1111/jnc.13213.PMID:26118771

Protective role of reactive astrocytes in brain ischemia. Li L, Lundkvist A, Andersson D, Wilhelmsson U, Nagai N, Pardo AC, Nodin C, Ståhlberg A, Aprico K, Larsson K, Yabe T, Moons L, Fotheringham A, Davies I, Carmeliet P, Schwartz JP, Pekna M, Kubista M, Blomstrand F, Maragakis N, Nilsson M, Pekny M.

J Cereb Blood Flow Metab. 2008 Mar;28(3):468-81.PMID:17726492

Increased neurogenesis and astrogenesis from neural progenitor cells grafted in the hippocampus of GFAP-/- Vim-/- mice. Widestrand A, Faijerson J, Wilhelmsson U, Smith PL, Li L, Sihlbom C, Eriksson PS, Pekny M.

Stem Cells. 2007 Oct;25(10):2619-27.PMID:17628017


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