Mechanobiology, mechanoepigenetics, tissue engineering designs
dynamic bioreactors/devices for imposing a combination of mechanical signals to cells in cultures
to observe/measure the "travel" of mechanical or similar signals within the cytoskeleton and/or through the nuclear envelope
Yannis F.Missirlis, “ Mechanoepigenetics”, frontiers in Cell and Developmental Biology, vol.4, article 113, October 2016.
Th.Tsapikouni and Y.F.Missirlis, “P-selectin /ligand unbinding force measured with Atomic Force Microscopy: Comparison of two chemical protocols for the tethering of single molecules”, Journal of Molecular Recognition, 24(5): 847-853, 2011.
Stergios Dermenoudis and Yannis Missirlis, “Design of a novel rotating wall bioreactor for the in vitro simulation of the mechanical environment of the endothelial function “, J.Biomechanics, 43(7):1426-1431,2010
Th. S. Tsapikouni and Y.F.Missirlis, “Measuring the force of single protein molecule detachment from surfaces with AFM”, Colloids and Surfaces B: Biointerfaces, 75(1): 252-259,2010.
A Foka, MG Katsikogianni, ED Anastassiou, I Spiliopoulou, YF Missirlis, “The combined effect of surface chemistry and flow conditions on Staphylococcus epidermidis adhesion and ica operon expression “, European Cells & Materials Journal, 24: 386-402, 2012.