CNR National Research Council of Italy - Institute of Molecular Genetics, Unit of Bologna

Lamins and laminopathies

Address

Via di Barbiano 1/10
I-40136 Bologna
Italy

Phone: +39 051 6366857
http://www.igm.cnr.it/igm-bologna/

Contacts

Head

Giovanna Lattanzi
Phone: +39 3407796461
Email: giovanna.lattanzi@cnr.it

Involved in

  • WG4 - Mechanobiological principles of rare and common diseases

General description research focus

The "Lamins and laminopathies" research group at the Unit of Bologna of the CNR Institute of Molecular Genetics is focused on cell biology of lamins and nuclear envelope proteins, regarding both basic cellular mechanisms and pathogenetic mechanisms of laminopathies. 

Imaging technologies available

  • Laser Scanning Confocal Microscopy (LSM / CLSM)
  • Total Internal Reflection Fluorescence Microscopy (TIRF)
  • Electron Microscopy
  • Live cell imaging

Equipment available

ZEISS EVo Scanning Electron Microscope

Jeol Transmission Electron Microscope

Nikon Laser Confocal Microscope

Expertise support provided to users

For all available technologies we provide:

- sample preparation

- observation of samles

- image analysis

- statistical analysis

Research topics directly investigated in research group

- Lamins and muscle differentiation

. Lamins and adipocyte differentiation

 -Lamins  and bone differentiation

- Lamins, emerin under stress conditions and in the ageing process

- Laminopathies: Hutchinson-Gilford Progeria, Mandibuloacral Dysplasia, Familial Prtial Lipodystrophy type 2, Emery-Dreifuss Muscular Dystrophy, COngenital Muscular Dystrophy - LMNA -related, Dilated Cardiomyopathy with Conduction Disorders (DCM1A).

Access rules research groups

The group is available for collaborations or services.

Please, ask at our e-mail address.