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Department of Biochemistry, Zurich University

Cryo-EM

Address

Winterthurer 190
CH 8057 Zurich
Switzerland

Phone:
https://www.bioc.uzh.ch/home/
https://www.bioc.uzh.ch/research/research-groups/medalia/

Contacts

Head

Ohad Medalia
Phone:
Email: omedalia@bioc.uzh.ch

Involved in

WG2 - Structural analysis of biomolecules involved in mechanobiology

General description research focus

The overall aim of our work is to understand the cellular remodeling of bio-macromolecules and structure-function relations of large protein machines during cellular processes, using three-dimensional (3D) microscopy approaches. Projects range from the development of molecular markers design to direct imaging of individual protein complexes and cytoskeleton organization to the retrieval of structures of large macromolecular complexes in situ, using 3D averaging of sub-tomograms from eukaryotic cells.