c/Rossello 161, sexta planta
The Neurobiology Unit investigates molecular mechanisms of neuronal death with the objective of identifying new therapeutic targets for the treatment of neurodegenerative diseases. Our research is focused in two main lines: 1) Molecular mechanisms of synapse elimination in models of Alzheimer's disease, 2) Regulation of mitochondrial DNA replication, transcription and transport in genetic models of Alzheimer’s and Parkinson’s diseases. Our group investigates the influence of mitochondrial fusion/ fission and transport processes on neuronal synapse loss in models of neurodegeneration. In addtion, our work aims to identify epigenetic mechanisms that regulate mitochondrial DNA transcription and replication during neurodegeneration.
Bio-Rad QX200 Digital PCR platform
Absolute quantification of gene transcription and copy number from sample preparation to data analyses.
9-11 September 2019, Trnava, Slovakia