IIBB/CSIC

Neurobiology Unit

Address

c/Rossello 161, sexta planta
08036 Barcelona
Spain

Phone: +34944648403
www.iibb.csic.es/en/research/51
www.iibb.csic.es/en/research/51

Contacts

Head

Ramon Trullas
Phone:
Email: ramon.trullas@iibb.csic.es

Involved in

  • WG3 - New methodologies to study mechanobiology of cells and tissues
  • WG4 - Mechanobiological principles of rare and common diseases

General description research focus

The Neurobiology Unit investigates molecular mechanisms of neuronal death with the objective of identifying new therapeutic targets for the treatment of neurodegenerative diseases. Our research is focused in two main lines: 1) Molecular mechanisms of synapse elimination in models of Alzheimer's disease, 2) Regulation of mitochondrial DNA replication, transcription and transport in genetic models of Alzheimer’s and Parkinson’s diseases. Our group investigates the influence of mitochondrial fusion/ fission and transport processes on neuronal synapse loss in models of neurodegeneration. In addtion, our work aims to identify epigenetic mechanisms that regulate mitochondrial DNA transcription and replication during neurodegeneration.

Imaging technologies available

Equipment available

Bio-Rad QX200 Digital PCR platform

Expertise support provided to users

Absolute quantification of gene transcription and copy number from sample preparation to data analyses.

Research topics directly investigated in research group

-

Access rules research groups

-