CNR Institute of Molecular Genetics Unit of Bologna

Nuclear envelope and Laminopathies

Address

Via di Barbiano 1/10
I-40136 Bologna
Italy

Phone: +39 0516366857
http://www.igm.cnr.it/1/igm-bologna/
http://www.igm.cnr.it/1/igm-bologna/research-activities/

Contacts

Head

Giovanna Lattanzi
Phone: +39 0516366857
Email: giovanna.lattanzi@cnr.it

Involved in

  • WG4 - Mechanobiological principles of rare and common diseases

General description research focus

Our research group is focused on laminopathies research with 3 main topics:

1) Progeroid laminopathies and prelamin A involvement in normal ageing

2) Muscular laminopathies 

3) Lipodystrophies and lamin and prelamin A involvement in adipocyte differentiation

Imaging technologies available

  • Laser Scanning Confocal Microscopy (LSM / CLSM)
  • Electron Microscopy

Equipment available

ZEISS EVO MA10 Scanning electron microscope

JEOL JEM-1011 Transmission Elelctron microsocpe

Nikon Confocal microscopy Time Lapse Resonant scanner Spectral detector TIRF microscopy N-SIM N-STORM

Expertise support provided to users

Sample preparation, imaging, image analysis, report of results

Research topics directly investigated in research group

Lamins

Nuclear envelope

Laminopathies

Chromatin organization

Muscle and adipocyte differentiation

Access rules research groups

facilities can be accessed in terms of scientific collaboration or as a custom activity.