University of Latvia Institute of Microbiology and Biotechnology

FT-IR spectroscopy research group



Mara Grube

Involved in

  • WG1 - Biophysics of cell and tissue structure
  • WG2 - Structural analysis of biomolecules involved in mechanobiology

General description research focus

Fourier transform infrared spectroscopy (FT-IR) methods are applied for studies of biosamples from microbioloy, biotechnology, and medicine. FT-IR spectra data anlyses are used for studies of cells, tissues, extracellular components and liquids, etc. For example,  FT-OR spectroscopy allows to evaluate the cell responce to environmental factors via macromolecular composition of cells.

Imaging technologies available

  • Fourier Transform Infrared Imaging (FTIR)

Equipment available

FT-IR Vertex 70 coupled with HTs-XT and Hyperion 2000, Bruker, Germany

Expertise support provided to users

FT-IR spectroscopy of bio-samples - sample preparation, data anlyses. qualitative and quantitative anlyses of cells, tissues, extracellular particles and liquids. studies of cell responces to environmental and/or other stress factors via the cell metabolism, qiuantitative chenges of total carbohydrates, nucleic acids, proteins oad/or lipids or toher specific componets iin cells.

Research topics directly investigated in research group

The responces of cells - microbial, yeast, bacterial, cancer, etc., to the growth environment incl nanopartices, and stress factors like hypoxia/normoxia via the macromolecular composition of cells and qualitative changes of the main macromolecular compnents.

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